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Results for "

Tubulysin M

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N7053
    Tubulysin M

    		ADC Cytotoxin Microtubule/Tubulin Cancer
    Tubulysin M is a highly cytotoxic anti-microtubule toxin (anti-microtubule toxins) that is synthesized as an ADC cytotoxin (ADC Cytotoxin). Tubulysin M can be isolated from the myxobacteria Archangium geophyra and Angiococcus disciformis. Tubulysin M displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the low nanomolar range. Tubulysin M inhibits microtubule/tubulin polymerization and leads to cell cycle arrest and apoptosis .
    <em>Tubulysin</em> <em>M</em>
  • HY-128896
    Nitro-PDS-Tubulysin M

    		Drug-Linker Conjugates for ADC Microtubule/Tubulin Cancer
    Nitro-PDS-Tubulysin M is a synthetic ADC drug-linker conjugate composed of the tubulin polymerization inhibitor Tubulysin M (an ADC Cytotoxin) and Nitro-PDS (an ADC linker).
    Nitro-PDS-<em>Tubulysin</em> <em>M</em>
  • HY-136313
    MC-VC-PAB-Tubulysin M

    		Drug-Linker Conjugates for ADC Microtubule/Tubulin Cancer
    MC-vc-PAB-Tubulysin M is a synthetic ADC drug-linker conjugate composed of the tubulin polymerization inhibitor Tubulysin M (an ADC Cytotoxin) (HY-N7053) and MC-vc-PAB (a cleavable ADC linker) .
    MC-VC-PAB-<em>Tubulysin</em> <em>M</em>
  • HY-128910
    MC-VC(S)-PABQ-Tubulysin M

    		Drug-Linker Conjugates for ADC Microtubule/Tubulin Cancer
    MC-VC(S)-PABQ-Tubulysin M is a synthetic ADC drug-linker conjugate composed of the tubulin polymerization inhibitor Tubulysin M (an ADC Cytotoxin) (HY-N7053) and MC-VC(S)- PABQ (an ADC linker) is connected. MC-VC(S)-PABQ-Tubulysin M is effective against multidrug-resistant lymphoma cell lines and tumors .
    MC-VC(S)-PABQ-<em>Tubulysin</em> <em>M</em>
  • HY-400684
    Tubulysin A intermediate-1

    		Others Cancer
    Tubulysin A intermediate-1 is an intermediate in the synthesis of the cytotoxic peptide Tubulysin A (HY-15995). Tubulysin A (TubA) is an antibiotic, anti-microtubule toxins, and apoptosis inducer isolated from myxobacteria. Tubulysin A has anti-angiogenic, anti-microtubule, anti-mitotic, and anti-proliferative activities. Tubulysin A arrests cells in the G2/M phase, effectively inhibits tubulin polymerization, and induces depolymerization of detached microtubules. Tubulysin A acts as an ADC cytotoxin (ADC Cytotoxin) to synthesize ADC .
    <em>Tubulysin</em> A intermediate-1

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